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Chemical collection and stock control for UK schools, universities and hospitals

Bisphenol A diglycidyl ether (CAS 1675-54-3): storage and disposal

Most holders know bisphenol A diglycidyl ether only as the base part of an epoxy embedding resin, used for electron microscopy blocks in university and histology labs, and found in some dental materials. Uncured, it irritates skin and eyes, may cause an allergic skin reaction and is toxic to aquatic life. Cured resin has a lower hazard than uncured resin, so the state it is in decides most of the handling.

CAS number
1675-54-3
Form
Liquid
Storage class
General
Signal word
Warning
Usual EWC code
16 05 06*
  • Harmful or irritant pictogramHarmful or irritant
  • Hazardous to the environment pictogramHazardous to the environment

What to do this week

  1. Check the label is readable and write down the opened date if it is not already there.
  2. Check it is stored as general stock and apart from the items listed under "Do not store with".
  3. If you no longer need it, add it to your disposal list so it goes on the next collection.

Safe storage in a school or lab

Electron microscopy suites may hold it as one bottle in a resin kit, alongside separately contained hardener and accelerator. Keep the components clearly identified and stored according to the supplier's instructions, away from heat sources such as embedding ovens. Keep those parts in their kit and clearly labelled, because a sticky unmarked bottle is the common find. Sensitisation is the real concern with stock like this: drips on bottle shoulders and on cupboard handles pass to the next person, and allergy can build up over time. A dedicated tray that catches drips helps, as do dated labels on arrival. Cold rooms are less helpful than they appear, since liquid epoxy can turn cloudy or crystallise when chilled. A dry, labelled store keeps it far enough from food supplies and general bench traffic.

How to tell it has deteriorated

Thick, slow-moving resin that barely shifts when the bottle is tilted is usually what you notice first, because the resin thickens as it ages. Dried amber runs down the outside and a cap glued in place are close behind. Neither is a disaster, but a stuck cap should stay stuck: do not force it. Cloudiness or crystals can also appear after cold storage, which is a physical change in the liquid and tells you little about age. A label with no date, or a kit missing its hardener or accelerator, makes it harder to describe. Faint yellowing is common in old resin, and unexpected colour change should be noted. Few other visual signs are reliable.

How it must be disposed of

By specialist collection only. It never goes down the drain or into general waste. It is normally packed in a non-regulated or low hazard laboratory pack with compatible chemicals.

Specialist collection is how uncured resin leaves the site, and the part-used kit bottle is the usual item. It is tempting to mix leftovers with hardener so that a solid block can be thrown away, but never cure it for that reason, and never put uncured resin in a sink, a drain, a skip or a general waste bin. It is toxic to aquatic life, and resin wastes need accurate description. List resin, hardener and accelerator as separate items with their volumes. Say if you also hold embedded blocks, which are cured and carry a lower hazard, as they need not be grouped with liquids. University labs would normally expect 16 05 06*, and hospital histology labs 18 01 06*.

Waste codes and transport details for Bisphenol A diglycidyl ether
EWC code, laboratory chemicals16 05 06*
Discarded organic chemical, not a laboratory pack16 05 08*
Human healthcare setting18 01 06*
Hazardous wasteYes

The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.

Common quantities we collect

Usually held as: epoxy embedding resin.

Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.

Where it is commonly held

Hazard statements

  • H315 Causes skin irritation.
  • H317 May cause an allergic skin reaction.
  • H319 Causes serious eye irritation.
  • H411 Toxic to aquatic life with long lasting effects.
Precautionary statements
  • P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264 Wash hands and exposed skin thoroughly after handling.
  • P264+P265 Wash hands and exposed skin thoroughly after handling. Do not touch eyes.
  • P272 Contaminated work clothing should not be allowed out of the workplace.
  • P273 Avoid release to the environment.
  • P280 Wear protective gloves, protective clothing, eye protection and face protection.
  • P302+P352 IF ON SKIN: Wash with plenty of water.
  • P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321 Specific treatment (see supplemental first aid instruction on this label).
  • P332+P317 If skin irritation occurs: Get medical help.
  • P333+P317 If skin irritation or rash occurs: Get medical help.
  • P337+P317 If eye irritation persists: Get medical help.
  • P362+P364 Take off contaminated clothing. And wash it before reuse.
  • P391 Collect spillage.
  • P501 Dispose of contents and container in accordance with local, regional, national and international regulations.

Substance as classified, dilutions may differ.

Questions

Can we mix leftover resin with hardener and bin the cured block?

Do not do this as a way of disposing of it. Mixing a bottle of old resin can run hot in a way that a thin embedding block does not, and it counts as treating the waste. List the resin and hardener separately and ask for them to be collected.

Our old resin has gone very thick. Is it still collected as a liquid?

Describe it as aged, thickened uncured resin and give the size of the bottle. Thickening is normal for old stock and does not stop a collection. It remains uncured resin with the same skin and aquatic concerns, and it should not be heated or thinned to make it pour.

Do finished resin blocks and old specimen blocks need the same disposal?

Not the same, because cured resin has a lower hazard than uncured resin. Still mention them in your description, along with anything embedded in them and any heavy metal stains used. Blocks with human or animal tissue may raise separate questions, so say what they contain.

Does the embedding resin need a refrigerator?

Follow the supplier's kit instructions, as some embedding kits ask for cold storage of mixed components. Base resin itself can go cloudy or crystallise in the cold, which often surprises people. If you do keep any in a refrigerator, label it clearly and keep it well away from anything food related.

Guidance only. Check your own risk assessment and your supplier's safety data sheet.

Hazard data source: PubChem GHS Classification, retrieved 31 Oct 2026. Formula C21H24O4. EC number 216-823-5.

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