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Chemical collection and stock control for UK schools, universities and hospitals

Cetrimonium bromide (CAS 57-09-0): storage and disposal

Cetrimonium bromide, known to most bench staff as CTAB, is a white waxy powder held in university and pathology labs, mostly for extracting DNA from plant and other tough samples. The recorded hazards include serious eye damage, organ damage from prolonged exposure and very toxic aquatic effects with long lasting results. Its fine dust and its behaviour with other detergents are what decide how it is stored.

CAS number
57-09-0
Form
Solid
Storage class
General
Signal word
Danger
Usual EWC code
16 05 06*
  • Corrosive pictogramCorrosive
  • Harmful or irritant pictogramHarmful or irritant
  • Serious health hazard pictogramSerious health hazard
  • Hazardous to the environment pictogramHazardous to the environment

What to do this week

  1. Check the label is readable and write down the opened date if it is not already there.
  2. Check it is stored as general stock and apart from the items listed under "Do not store with".
  3. If you no longer need it, add it to your disposal list so it goes on the next collection.

Safe storage in a school or lab

The hazard that decides where CTAB goes is serious eye damage, which makes it a stock to keep low down in a closed container with the lid screwed fully home, never loose in a weighing area. It is a cationic surfactant, so it forms a precipitate with anionic detergents such as sodium dodecyl sulfate. In a molecular biology store keep CTAB on a different shelf from SDS and from detergent-based extraction buffers, because a leak between the two makes a sticky solid that is hard to describe. Keep it dry. Label bottles of the powder with the opening date, and note when any made-up solution on the shelf was prepared by someone else.

How to tell it has deteriorated

Normal CTAB is a white to cream powder, fine and slightly waxy, that flows when a bottle is tilted. What a technician sees first on an old jar is caking. The powder draws moisture and sets into soft lumps or a hard cake that sticks to the bottle wall, and a yellowed colour or a damp surface follows. Dust on the thread and shelf is common because the fine powder escapes every time the cap is opened. Check the label for staining and the cap for cracks. A cake that cannot be broken without force should not be forced, and a jar that has leaked onto the shelf should be recorded and left alone.

How it must be disposed of

By specialist collection only. It never goes down the drain or into general waste. It is normally packed in a non-regulated or low hazard laboratory pack with compatible chemicals.

Record the jar as labelled, say whether it is the pure powder and give an approximate weight. With serious eye damage, organ effects and aquatic hazards on record, it is packed as a hazardous solid into a lab pack with compatible organic solids and collected by a registered carrier. The code in a university lab is 16 05 06*, with 16 05 08* where it is a discarded organic chemical outside a pack and 18 01 06* in a human healthcare setting. Keep it clear of the general waste, a sink or a drain, and do not rinse the jar out first because the aquatic classification is the reason.

Waste codes and transport details for Cetrimonium bromide
EWC code, laboratory chemicals16 05 06*
Discarded organic chemical, not a laboratory pack16 05 08*
Human healthcare setting18 01 06*
Hazardous wasteYes

The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.

Common quantities we collect

Usually held as: solid.

Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.

Where it is commonly held

Hazard statements

  • H302 Harmful if swallowed.
  • H315 Causes skin irritation.
  • H318 Causes serious eye damage.
  • H335 May cause respiratory irritation.
  • H373 May cause damage to organs through prolonged or repeated exposure.
  • H410 Very toxic to aquatic life with long lasting effects.
Precautionary statements
  • P260 Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264 Wash hands and exposed skin thoroughly after handling.
  • P264+P265 Wash hands and exposed skin thoroughly after handling. Do not touch eyes.
  • P270 Do not eat, drink or smoke when using this product.
  • P271 Use only outdoors or in a well-ventilated area.
  • P273 Avoid release to the environment.
  • P280 Wear protective gloves, protective clothing, eye protection and face protection.
  • P301+P317 IF SWALLOWED: Get medical help.
  • P302+P352 IF ON SKIN: Wash with plenty of water.
  • P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317 Get medical help.
  • P319 Get medical help if you feel unwell.
  • P321 Specific treatment (see supplemental first aid instruction on this label).
  • P330 Rinse mouth.
  • P332+P317 If skin irritation occurs: Get medical help.
  • P362+P364 Take off contaminated clothing. And wash it before reuse.
  • P391 Collect spillage.
  • P403+P233 Store in a well-ventilated place. Keep container tightly closed.
  • P405 Store locked up.
  • P501 Dispose of contents and container in accordance with local, regional, national and international regulations.

Substance as classified, dilutions may differ.

Questions

Why should CTAB not be kept next to SDS?

CTAB is a cationic surfactant and SDS is anionic, so the two form a precipitate when they meet. A leak between neighbouring bottles would leave a sticky solid that is awkward to describe and clean up. Separate shelves avoid it.

Our CTAB has set into a hard lump. Is it still usable?

Caking shows moisture has entered, so the stock may no longer be accurate to weigh. Do not chip it out with force because the dust is harmful to the eyes. Record it for collection if it is not wanted.

Which hazards matter most for CTAB waste?

The recorded statements include serious eye damage, organ damage on prolonged exposure and very toxic effects to aquatic life with long lasting results. They are the reason it is collected as hazardous waste and never put to a drain.

Guidance only. Check your own risk assessment and your supplier's safety data sheet.

Hazard data source: PubChem GHS Classification, retrieved 31 Oct 2026. Formula C19H42BrN. EC number 200-311-3.

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