Skip to content

Chemical collection and stock control for UK schools, universities and hospitals

Diazepam (CAS 439-14-5): storage and disposal

Diazepam is a benzodiazepine held as tablets and injection by hospital pharmacies, clinics and veterinary practices. It is a Class C controlled drug under Schedule 4 Part 1 of the Misuse of Drugs Regulations 2001, and as a substance it is classified as toxic if swallowed and in contact with skin. Controlled status decides the handling more than its chemistry does: the accountable officer or responsible pharmacist makes the call, and this site only deals with it by manual enquiry.

CAS number
439-14-5
Form
Solid
Storage class
Toxic
Signal word
Danger
Usual EWC code, laboratory stock
16 05 06*
  • Acute toxicity pictogramAcute toxicity

This chemical is a manual enquiry

This is a controlled drug. Controlled drugs have their own legal requirements, which depend on the schedule and can cover storage, witnessing and destruction, so they cannot be priced through a standard form.

UK Misuse of Drugs Regulations 2001: Schedule 4 Part 1, Class C.

It cannot be priced through a form. Please do not open or move it. Call us or send an enquiry and we will talk through the next step, which depends on what it is. Keep following your own procedures for controlled drugs, radioactive materials, gases and asbestos.

What to do this week

  1. Leave it where it is. If it looks old, crystalline or damaged, do not open or move it and keep people away from the shelf. If there is immediate danger, such as a leak, fumes or a fire, leave the area and call 999.
  2. Write down the label wording, the rough age and where it is stored, from a safe distance.
  3. Send us those details, and a photo if you can take one without touching it.

Safe storage in a school or lab

Keep diazepam stock separate from incompatible chemicals, including oxidisers, and follow the product's storage requirements. Tablets and ampoules should be stored securely under the site's medicines procedure, with appropriate stock records maintained. Schedule 4 Part 1 does not itself require a statutory controlled drugs register or controlled drugs cabinet. The stock that causes trouble is the stock that has drifted out of that cupboard: ampoules in a seizure kit, an anaesthetic trolley or a vet's call-out bag, where heat and daylight reach them and nobody counts them. Diazepam is known to be taken up by some plastics, and the injection dislikes light, so ampoules are best kept in their original carton instead of loose in a plastic tray or bag.

How to tell it has deteriorated

A carton with a faded expiry date, or loose ampoules with no box at all, is usually the first thing anyone notices. Colour alone tells you little until you know which product you hold, because diazepam injection comes either as a clear, faintly yellow solution or as a milky white emulsion. Cloudiness or crystals in the clear type, or an oily layer separating out of the emulsion, mean the contents have changed. Tablets give few visible signs: look for crumbling, damp marks, split blisters or tablets moved into an unlabelled pot. A count that no longer matches the stock record is the sign that matters most, and it goes straight to the accountable officer.

How it is disposed of

This does not go through our standard collection route. It is arranged by manual enquiry, and never goes down the drain or into general waste.

Stock leaves the site only after a manual enquiry, since diazepam is not quoted online and a general chemical collection does not cover it. Destruction of controlled stock falls under the Misuse of Drugs Regulations 2001. Routine Schedule 4 Part 1 stock destruction does not normally need an authorised witness, although local procedures may ask for one, so the accountable officer or responsible pharmacist decides first. In your enquiry, give the form, the number of ampoules or tablets, the expiry date and whether the stock came back from a patient. Veterinary holders normally use 18 02 08, which differs from the code normally used in human healthcare, so say which you are. A store assessment helps where old cartons have built up. Leave everything locked where it is meanwhile, and never empty ampoules into a sink.

Waste codes for Diazepam
Usual EWC code, laboratory stock16 05 06*
Discarded organic chemical, not a laboratory pack16 05 08*
Human healthcare setting18 01 09
Veterinary setting18 02 08
Usually classed as hazardous wasteYes

The code depends on where the waste came from and what it contains, and classifying it is the producer's duty. Use the waste code finder to see why.

Do not store with

  • OxidiserToxic and oxidising stock are stored apart. A reaction could release toxic vapours.
  • AcidToxic stock is stored apart from acids. Several toxic salts release toxic gas in contact with acid.

Named chemicals to keep apart

  • Acetic acidToxic stock is stored apart from acids. Several toxic salts release toxic gas in contact with acid.
  • Calcium hypochloriteToxic and oxidising stock are stored apart. A reaction could release toxic vapours.
  • Hydrochloric acidToxic stock is stored apart from acids. Several toxic salts release toxic gas in contact with acid.
  • Hydrogen peroxideToxic and oxidising stock are stored apart. A reaction could release toxic vapours.
  • Nitric acidToxic stock is stored apart from acids. Several toxic salts release toxic gas in contact with acid.
  • Potassium nitrateToxic and oxidising stock are stored apart. A reaction could release toxic vapours.
  • Potassium permanganateToxic and oxidising stock are stored apart. A reaction could release toxic vapours.
  • Sulfuric acidToxic stock is stored apart from acids. Several toxic salts release toxic gas in contact with acid.

Common quantities

Usually held as: injection, tablets.

Tell us the container size and how many you hold. An estimate is enough to start with, and some items cannot be priced until someone has looked at them.

Where it is commonly held

Hazard statements

  • H301 Toxic if swallowed.
  • H311 Toxic in contact with skin.
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing.
  • P264 Wash hands and exposed skin thoroughly after handling.
  • P270 Do not eat, drink or smoke when using this product.
  • P280 Wear protective gloves, protective clothing, eye protection and face protection.
  • P301+P316 IF SWALLOWED: Get emergency medical help immediately.
  • P302+P352 IF ON SKIN: Wash with plenty of water.
  • P316 Get emergency medical help immediately.
  • P321 Specific treatment (see supplemental first aid instruction on this label).
  • P330 Rinse mouth.
  • P361+P364 Take off immediately all contaminated clothing. And wash it before reuse.
  • P405 Store locked up.
  • P501 Dispose of contents and container in accordance with local, regional, national and international regulations.

Substance as classified, dilutions may differ.

Questions

We have found diazepam ampoules in an old emergency bag. What happens now?

Tell the responsible pharmacist or accountable officer straight away and follow their direction on securing the ampoules. Note the strength, quantity and expiry date from the label, and check them against any record. An unexplained find is a records issue as well as a waste issue, so it should not simply be added to a clear-out.

Is a diazepam tablet as dangerous as the pure powder?

Not necessarily. The toxic classification describes the substance itself, and a finished tablet or ampoule contains much less of it, so it may be less hazardous. It still needs care, and its controlled status applies equally to every form you hold, from a single tablet to a reference powder.

Does a veterinary practice use the same waste code as a hospital?

Usually not. Medicines from a veterinary setting normally take 18 02 08, while 18 01 09 normally fits human healthcare. Say in your enquiry which applies, and mention any reference powder separately, because a discarded laboratory chemical is described differently from finished medicines.

Can a diazepam ampoule that went cloudy still be held with in-date stock?

It should stay in the locked arrangement, clearly marked as not for use and recorded, until the responsible pharmacist or accountable officer decides what happens. Nobody should open it to look closer. Its changed appearance goes in the enquiry, along with the batch and expiry shown on the carton.

Guidance only. Check your own risk assessment and your supplier's safety data sheet.

Hazard data source: PubChem GHS Classification, retrieved 31 Oct 2026. Formula C16H13ClN2O. EC number 207-122-5.

Manual enquiry Add to register