Fluorescein (CAS 2321-07-5): storage and disposal
A bright orange-red powder that glows yellow-green once it is in solution, fluorescein is held as loose powder in teaching and research stores and as sodium salt ophthalmic strips in clinics and pharmacies. Its classification is serious eye irritation, so dust and splashes near the face are the main concern. The form decides how the stock is described: a stock bottle, a part-used pot and a box of expired strips are three different entries.
- CAS number
- 2321-07-5
- Form
- Solid
- Storage class
- General
- Signal word
- Warning
- Usual EWC code
- 16 05 06*
Harmful or irritant
What to do this week
- Check the label is readable and write down the opened date if it is not already there.
- Check it is stored as general stock and apart from the items listed under "Do not store with".
- If you no longer need it, add it to your disposal list so it goes on the next collection.
Safe storage in a school or lab
In school and university prep rooms the stock is powder in a small screw-cap bottle, and in clinic and pharmacy cupboards it is individually wrapped strips. Keep the bottle capped and labelled on a dry shelf and leave strips in their wrappers until the moment of use. It is general stock, so no special cabinet is needed, but the dye is intensely coloured and spilt powder travels on gloves, so a tray under the bottle is worth having. Strips belong with patient-facing supplies rather than with bench chemicals, with the date of receipt written on the box. Keep goggles within reach of the shelf, because the eye is where this powder does its harm.
How to tell it has deteriorated
Good fluorescein powder is a uniform orange-red, dry and free flowing. Clumping, a damp feel or a darker crust inside the neck means moisture has got in, and an orange stain on the cap or shelf shows powder has escaped past the thread. Beyond that the substance gives few visible signs of age, so the container tells you more than the colour does: a faded label, a cracked bottle or no record of when it arrived are reasons enough to list it for collection. For strips, look at the sachet. Torn or damp wrappers, discoloured paper and a printed expiry date that has passed all mean the strips are now waste stock and should not go back into clinical use.
How it must be disposed of
By specialist collection only. It never goes down the drain or into general waste. It is normally packed in a non-regulated or low hazard laboratory pack with compatible chemicals.
Record what is physically in the container before asking for a collection: loose powder, sodium salt strips or both, how many boxes and whether any are opened. Stock from a prep room or research store is described under the discarded laboratory chemical code 16 05 06*, while a clinic or pharmacy clearing expired strips would normally use 18 01 06*. Strips stay in their boxes and powder bottles stay sealed, so the carrier can group them with other dry laboratory chemicals in a lab pack. Washing residue down a sink or tipping powder into general waste is not an option, and bright staining on the packaging is a reason to bag it separately, not to rinse it.
| EWC code, laboratory chemicals | 16 05 06* |
|---|---|
| Discarded organic chemical, not a laboratory pack | 16 05 08* |
| Human healthcare setting | 18 01 06* |
| Hazardous waste | Yes |
The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.
Common quantities we collect
Usually held as: solid, sodium salt ophthalmic strips.
Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.
Where it is commonly held
Hazard statements
- H319 Causes serious eye irritation.
Precautionary statements
- P264 Wash hands and exposed skin thoroughly after handling.
- P264+P265 Wash hands and exposed skin thoroughly after handling. Do not touch eyes.
- P270 Do not eat, drink or smoke when using this product.
- P280 Wear protective gloves, protective clothing, eye protection and face protection.
- P301+P317 IF SWALLOWED: Get medical help.
- P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P330 Rinse mouth.
- P337+P317 If eye irritation persists: Get medical help.
- P501 Dispose of contents and container in accordance with local, regional, national and international regulations.
Substance as classified, dilutions may differ.
Questions
Can expired fluorescein eye strips go in clinical waste?
No, they are collected as chemical stock and described under the healthcare setting code, not put in a general or clinical bin. Keep them in their sachets and boxes, note how many boxes there are and request a collection like any other chemical item.
Does fluorescein powder need a special cabinet?
No. It is general stock, so a closed, labelled bottle on a dry shelf is enough. Because it causes serious eye irritation, keep it low enough to handle safely, away from the bench edge, and with eye protection nearby.
How can I tell if an old bottle of fluorescein is still any good?
The powder shows few signs of age, so judge the container instead. Check the cap, the label, the date of receipt and whether the contents are dry. A damp, crusted or undated bottle should be listed for collection rather than kept.
Why does my prep room code differ from the pharmacy next door?
The code follows the setting that produced the waste. A school or university store uses the discarded laboratory chemical code, whereas human healthcare settings use their own healthcare entry. Say where the stock was held and it will be matched correctly.
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