Methylene blue (CAS 61-73-4): storage and disposal
Staining is the first thing anyone learns about methylene blue, and the stain rarely stays on the slide. Powder and 1% solution sit in school labs, pathology and histology rooms, pharmacy cupboards and veterinary practices. It is classified as harmful if swallowed and as causing serious eye damage, though stock in teaching labs is usually a weak solution. Where the bottle came from and what strength it holds decide how it is written up for collection.
- CAS number
- 61-73-4
- Form
- Solid
- Storage class
- General
- Signal word
- Danger
- Usual EWC code
- 16 05 06*
Corrosive
Harmful or irritant
What to do this week
- Check the label is readable and write down the opened date if it is not already there.
- Check it is stored as general stock and apart from the items listed under "Do not store with".
- If you no longer need it, add it to your disposal list so it goes on the next collection.
Safe storage in a school or lab
Keep methylene blue away from the staff kitchen and any food or drink, because it is harmful if swallowed, and away from white powders and paper stock, because the dye marks whatever it touches. Stand powder and 1% solution bottles upright on a tray that catches drips and shows blue at once. Serious eye damage is the more pressing hazard, so goggles belong where the bottle is kept, not in another room. In pharmacy and veterinary cupboards, leave containers in their outer boxes so the label stays legible and is not stained by a neighbouring leak. Date each bottle on arrival and note when it was opened.
How to tell it has deteriorated
Start with the cap and label, because methylene blue announces itself there. A blue ring around the neck, a stained label or blue marks on the shelf below mean the seal has been leaking or the bottle has been handled with dirty gloves. The dye is so dark that even slight seepage looks dramatic, so a stain points to a loose cap rather than to spoilage. Powder that has become lumpy or damp shows moisture got in. A solution with a dried crust at the neck or a visibly lower level has lost water through a poor seal. Beyond these the substance gives few reliable signs of age, so a missing label or unknown date decides more than colour.
How it must be disposed of
By specialist collection only. It never goes down the drain or into general waste. It is normally packed in a non-regulated or low hazard laboratory pack with compatible chemicals.
The code that fits a school or university prep room is 16 05 06*, a pathology lab or hospital pharmacy clearing stock uses 18 01 06*, and a veterinary practice uses 18 02 05*. Say which setting the stock came from, because the code follows the place and not the dye. List powder and 1% solution as separate lines and flag any bottle that is leaking or stained, so it can be packed in a sealed outer container with compatible items. Pouring leftover solution down a sink is not allowed however weak it looks, and nobody should try to bleach it or otherwise treat it first.
| EWC code, laboratory chemicals | 16 05 06* |
|---|---|
| Discarded organic chemical, not a laboratory pack | 16 05 08* |
| Human healthcare setting | 18 01 06* |
| Veterinary setting | 18 02 05* |
| Hazardous waste | Yes |
The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.
Common quantities we collect
Usually held as: solid, 1% solution.
Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.
Where it is commonly held
Hazard statements
- H302 Harmful if swallowed.
- H318 Causes serious eye damage.
Precautionary statements
- P264 Wash hands and exposed skin thoroughly after handling.
- P264+P265 Wash hands and exposed skin thoroughly after handling. Do not touch eyes.
- P270 Do not eat, drink or smoke when using this product.
- P273 Avoid release to the environment.
- P280 Wear protective gloves, protective clothing, eye protection and face protection.
- P301+P317 IF SWALLOWED: Get medical help.
- P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317 Get medical help.
- P330 Rinse mouth.
- P501 Dispose of contents and container in accordance with local, regional, national and international regulations.
Substance as classified, dilutions may differ.
Questions
Which waste code applies to methylene blue from a veterinary practice?
Veterinary stock normally takes 18 02 05*, whereas a school or university prep room uses 16 05 06* and human healthcare settings use 18 01 06*. Tell the collector where the stock was held and the entry will be matched to it.
Is the 1% solution classed the same as the powder?
Not necessarily. A weak solution may be less hazardous than the powder, so do not assume the same classification. The supplier safety data sheet for that product decides. Either way it is still chemical waste and is described with its strength and container size.
Does methylene blue need a locked cabinet?
Its storage class is general stock, so no locked cabinet is set out for it. Because it is harmful if swallowed and causes serious eye damage, many sites still keep it in a closed, labelled cupboard away from food, with a stock record.
How long can a bottle sit on the shelf?
There is no set shelf life, so judge by condition: cap, label, damp or crusted powder and a falling level. A bottle with no date should be recorded as of unknown age and listed for collection rather than kept indefinitely.
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