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Chemical collection and stock control for UK schools, universities and hospitals

Permethrin (CAS 52645-53-1): storage and disposal

A pharmacy shelf with lotion or cream for skin parasites and a veterinary store with spot-on pipettes both hold permethrin, a synthetic insecticide held as a solid or in a ready-made topical product. It is classified as harmful if swallowed or inhaled, as possibly causing an allergic skin reaction, and as very toxic to aquatic life with long lasting effects.

CAS number
52645-53-1
Form
Solid
Storage class
General
Signal word
Warning
Usual EWC code
16 05 06*
  • Harmful or irritant pictogramHarmful or irritant
  • Hazardous to the environment pictogramHazardous to the environment

What to do this week

  1. Check the label is readable and write down the opened date if it is not already there.
  2. Check it is stored as general stock and apart from the items listed under "Do not store with".
  3. If you no longer need it, add it to your disposal list so it goes on the next collection.

Safe storage in a school or lab

Pharmacy and vet stock look very different, and the practical points differ. A pharmacy keeps lotion and cream in cartons on a general shelf, away from food and heat, with the aquatic classification in mind if a bottle breaks. A veterinary practice keeps pipettes in their cartons in a separate place from the retail display, and does not leave them on a windowsill or near the radiator. Bulk solid, if a lab holds it, is held in a closed labelled jar with a date. Because it may cause an allergic skin reaction, anyone wiping up a leaking bottle should avoid bare-handed contact. Date opened packs and rotate stock.

How to tell it has deteriorated

Lotions, creams and spot-on liquids should be even in texture and colour. A cream that has separated or hardened, a lotion with an oily layer, a bottle with a crusted neck, a swollen or split tube and a sticky carton are the visible signs. Pipettes should be sealed and dry, so a split tip or damp foil is a fault. Little else shows as it ages, so a jar of powder is checked for caking, a damp patch under the lid and a faded label. Any product past its date, undated or leaking is stock to list for collection.

How it must be disposed of

By specialist collection only. It never goes down the drain or into general waste. It is normally packed in a non-regulated or low hazard laboratory pack with compatible chemicals.

The aquatic classification is the main reason lotion is never tipped into a drain, however small the volume of lotion left in a bottle appears. UN 3077 is associated with environmentally hazardous solid permethrin. Liquid formulations require their own transport classification, which the collection supplier confirms. The usual waste codes are 16 05 06* for discarded laboratory chemical stock, 18 01 09 for applicable human healthcare medicines and 18 02 08 for applicable veterinary medicines. List each bottle, tube or pipette with product name, strength, count and condition, noting any that leak. The paperwork follows the waste classification confirmed for the particular product and setting. Expired stock is not put into the clinical bin or the general bin, and nobody should empty it first. A registered carrier collects it.

Waste codes and transport details for Permethrin
EWC code, laboratory chemicals16 05 06*
Discarded organic chemical, not a laboratory pack16 05 08*
Human healthcare setting18 01 09
Veterinary setting18 02 08
Hazardous wasteYes

The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.

Common quantities we collect

Usually held as: spot-on, topical.

Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.

Where it is commonly held

Hazard statements

  • H302 Harmful if swallowed.
  • H317 May cause an allergic skin reaction.
  • H332 Harmful if inhaled.
  • H410 Very toxic to aquatic life with long lasting effects.
Precautionary statements
  • P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264 Wash hands and exposed skin thoroughly after handling.
  • P270 Do not eat, drink or smoke when using this product.
  • P271 Use only outdoors or in a well-ventilated area.
  • P272 Contaminated work clothing should not be allowed out of the workplace.
  • P273 Avoid release to the environment.
  • P280 Wear protective gloves, protective clothing, eye protection and face protection.
  • P301+P317 IF SWALLOWED: Get medical help.
  • P302+P352 IF ON SKIN: Wash with plenty of water.
  • P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P317 Get medical help.
  • P321 Specific treatment (see supplemental first aid instruction on this label).
  • P330 Rinse mouth.
  • P333+P317 If skin irritation or rash occurs: Get medical help.
  • P362+P364 Take off contaminated clothing. And wash it before reuse.
  • P391 Collect spillage.
  • P501 Dispose of contents and container in accordance with local, regional, national and international regulations.

Substance as classified, dilutions may differ.

Questions

What happens to leftover permethrin lotion?

It is classified as very toxic to aquatic life with long lasting effects, so even small volumes are collected and are never put into a drain. Keep it in its labelled bottle and list it for specialist collection.

Is the pharmacy lotion the same waste as the vet spot-on?

They contain the same substance in different products, so list each by its own product name, strength and form. The code can differ with setting, so say if you are a pharmacy or a veterinary practice.

How can we tell a tube or pipette has gone off?

Look for separation, hardening, an oily layer, split tubes, sticky cartons and damaged tips, and check the date. Few other changes are visible, so the container tells you most.

Why does the paperwork mention UN 3077?

UN 3077 is the transport entry associated with environmentally hazardous solid permethrin. The collection supplier confirms the appropriate classification for each product, including liquid preparations. You do not need to work it out, only to describe the product accurately.

Guidance only. Check your own risk assessment and your supplier's safety data sheet.

Hazard data source: PubChem GHS Classification, retrieved 31 Oct 2026. Formula C21H20Cl2O3. EC number 258-067-9.

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