Tripotassium EDTA (CAS 17572-97-3): storage and disposal
Pathology laboratories and clinics meet this chemical mainly as the anticoagulant additive in blood collection tubes, and sometimes as loose powder for preparing them. It is classified with a Warning signal word for serious eye irritation, harm if inhaled and possible organ damage after prolonged or repeated exposure. Expired or surplus unused stock therefore leaves by specialist collection, and the way it is held matters more than the small amounts suggest.
- CAS number
- 17572-97-3
- Form
- Solid
- Storage class
- General
- Signal word
- Warning
- Usual EWC code
- 16 05 06*
Harmful or irritant
Serious health hazard
What to do this week
- Check the label is readable and write down the opened date if it is not already there.
- Check it is stored as general stock and apart from the items listed under "Do not store with".
- If you no longer need it, add it to your disposal list so it goes on the next collection.
Safe storage in a school or lab
Blood tube additive stock arrives boxed, and the tubes are best kept in their original cartons so the printed expiry date stays with them. Because the classification includes harm if inhaled, any loose powder should be in a closed container on the general shelf, apart from food and drink areas, with the lid screwed down after every use. Unused tubes belong in the dry, labelled stock cupboard of the pathology laboratory or clinic. Tubes already used for blood are a clinical waste matter and should not be mixed up with this unused chemical stock. Date stock on arrival, rotate it, and keep powder away from anything that would be spilled over it, such as open reagent trays.
How to tell it has deteriorated
On a shelf, an unopened tube looks like a plastic tube with a stopper and a thin coating or small deposit of white additive on the wall. Old tubes may show a cracked stopper, a loose label or a printed expiry date that has passed, and vacuum tubes can lose their draw as they age. The additive itself shows few visible signs, so do not rely on appearance. Loose powder that has clumped or looks damp has taken in moisture. General checks also apply, including faded labels, staining around a cap, a failed seal and a missing stock record. Anything that cannot be identified should be left in place, recorded and held for collection.
How it must be disposed of
By specialist collection only. It never goes down the drain or into general waste. It is normally packed in a non-regulated or low hazard laboratory pack with compatible chemicals.
Unused tubes and powder must not go into a sink, a drain, a general waste bin or a skip, and nobody should empty the additive out of tubes or treat it beforehand. Collection is by specialist route only. Boxed tubes pack easily with other small items, while loose powder needs its own sealed container, so say which you hold. The classification means a hazardous waste consignment note applies. Record the approximate number of boxes, the expiry dates if readable and the setting, because a clinic and a pathology laboratory may be described under different waste codes. Keep tubes that have held blood out of the same consignment entirely.
| EWC code, laboratory chemicals | 16 05 06* |
|---|---|
| Discarded organic chemical, not a laboratory pack | 16 05 08* |
| Human healthcare setting | 18 01 06* |
| Hazardous waste | Yes |
The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.
Common quantities we collect
Usually held as: blood tube additive.
Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.
Where it is commonly held
Hazard statements
- H319 Causes serious eye irritation.
- H332 Harmful if inhaled.
- H373 May cause damage to organs through prolonged or repeated exposure.
Precautionary statements
- P260 Do not breathe dust, fume, gas, mist, vapours or spray.
- P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264 Wash hands and exposed skin thoroughly after handling.
- P264+P265 Wash hands and exposed skin thoroughly after handling. Do not touch eyes.
- P271 Use only outdoors or in a well-ventilated area.
- P280 Wear protective gloves, protective clothing, eye protection and face protection.
- P302+P352 IF ON SKIN: Wash with plenty of water.
- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317 Get medical help.
- P319 Get medical help if you feel unwell.
- P321 Specific treatment (see supplemental first aid instruction on this label).
- P332+P317 If skin irritation occurs: Get medical help.
- P337+P317 If eye irritation persists: Get medical help.
- P362+P364 Take off contaminated clothing. And wash it before reuse.
- P403+P233 Store in a well-ventilated place. Keep container tightly closed.
- P405 Store locked up.
- P501 Dispose of contents and container in accordance with local, regional, national and international regulations.
Substance as classified, dilutions may differ.
Questions
Can out of date blood tubes go in the general bin?
Unused tubes containing the additive are chemical waste and should not go in general waste. Keep them boxed and labelled for specialist collection. Tubes that have held blood are a separate clinical waste stream and should not be added to this.
Does a pathology laboratory need to treat the powder first?
No. Nobody should treat it or alter the contents. Keep it in its closed container, record the amount, and hold it for specialist collection. The classification includes harm if inhaled, so avoid handling loose powder more than necessary.
How long can we keep unused tubes?
Use the printed expiry date on the carton and the tube label, and the supplier instructions. If the date has passed or cannot be read, treat the tubes as waste, keep them boxed and arrange collection.
Is this the same as the disodium salt on the shelf?
No, they are separate entries. The tripotassium salt is classified for eye irritation, harm if inhaled and possible organ damage after repeated exposure. Check the label and record each salt separately in the stock list.
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