1,2-Dimethoxyethane (CAS 110-71-4): storage and disposal
1,2-Dimethoxyethane, sometimes called glyme, is a highly flammable ether solvent found in university synthetic chemistry labs, often in a septum-capped bottle. It may damage fertility and the unborn child, is harmful if inhaled, and irritates skin. It also forms explosive peroxides on storage. The opened date on the label, along with how the bottle has been used, decides whether anyone should handle it.
- CAS number
- 110-71-4
- Form
- Liquid
- Storage class
- Flammable
- Signal word
- Danger
- Usual EWC code
- 16 05 06*
Flammable
Harmful or irritant
Serious health hazard
This chemical is a manual enquiry
This can become unstable or explosive, especially if it is old or has dried out. Nobody should move it until someone competent has looked at it, so we start with a conversation and usually a store assessment.
Ether solvent: dangerous peroxides in old stock, and age cannot be judged from a web form.
It cannot be priced through a form. Please do not open or move it. Call us or send an enquiry and we will talk through the safe next step, which is often a store assessment.
What to do this week
- Leave it where it is. If it looks old, crystalline or damaged, do not open or move it and keep people away from the shelf.
- Write down the label wording, the rough age and where it is stored, from a safe distance.
- Send us those details, and a photo if you can take one without touching it.
Safe storage in a school or lab
Fire risk from the vapour sets its location, a ventilated fire-resistant cabinet with spill containment, but the reproductive hazard should shape who works with it. Staff planning a pregnancy or expecting a child need to know where it is held, so it should not sit unlabelled in a shared solvent cupboard. Containers should carry opened dates, with a review 12 months after opening. Group members tend to pass a bottle between projects until nobody knows its history, and that is the moment to record who owns it. Hydrogen peroxide, permanganate, dichromate, chlorate, hypochlorite and chromium trioxide must stay apart, as this ether can ignite or explode with them. If anyone chills it, only a spark-free refrigerator will do.
How to tell it has deteriorated
Normal stock is a clear, colourless, thin liquid. Abnormal is harder to spot, as it gives few visual signs while peroxides build, so an unremarkable appearance is no proof of safety. The cap and label do most of the telling: a softened or heavily pierced septum shows repeated air exposure, and a missing opened date leaves the bottle's age unknown. Crystals around the cap or in the liquid, a viscous layer or a failed seal all point to serious trouble. If a bottle is old, undated or shows any warning sign, do not move it, do not open it, and get a specialist assessment. Peroxide testing is for competent staff only, and nobody should test a bottle already showing warning signs.
Forms explosive peroxides on storage.
This can form peroxides as it ages, especially after opening. Age and the opened date matter more than appearance, so a container with no opened date should be treated as old.
Review after 12 months: Review interval after opening from the cited peroxide former lists, not an expiry date from a manufacturer. Class C and all other chemicals are left null.
How it must be disposed of
This does not go through our standard collection route. It is arranged by manual enquiry, and never goes down the drain or into general waste.
Code 16 05 06* normally applies, but the code does not settle how it goes, because this ether is not quoted online and not accepted through the online quote path. Age cannot be judged from a web form, so a manual enquiry comes first, with the opened date, cap type and how full it seems. A store assessment is recommended, and a competent chemist decides in person, or an explosives or emergency specialist if warning signs are present. Do not open it, move it to a tidier shelf, or try to make it safe. It must never go into a sink or drain. Group labs clearing a departing member's bench should list each bottle separately, as a shared history is rarely a known one.
| EWC code, laboratory chemicals | 16 05 06* |
|---|---|
| Discarded organic chemical, not a laboratory pack | 16 05 08* |
| Hazardous waste | Yes |
20 01 13* (solvents) belongs to municipal collections and is shown for reference only. It is not the normal code for a laboratory collection.
The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.
Do not store with
- OxidiserOxidisers can ignite flammable materials or make a fire far more intense.
- AcidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- CorrosiveA leak of corrosive stock can break down flammable containers and feed a fire.
Named chemicals to keep apart
- Acetic acidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- Calcium hypochloritePeroxide forming ethers can ignite or explode with strong oxidisers.
- Chromium trioxidePeroxide forming ethers can ignite or explode with strong oxidisers.
- Hydrochloric acidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- Hydrogen peroxidePeroxide forming ethers can ignite or explode with strong oxidisers.
- Nitric acidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- Potassium chloratePeroxide forming ethers can ignite or explode with strong oxidisers.
- Potassium dichromatePeroxide forming ethers can ignite or explode with strong oxidisers.
Show 7 more
- Potassium nitrateOxidisers can ignite flammable materials or make a fire far more intense.
- Potassium permanganatePeroxide forming ethers can ignite or explode with strong oxidisers.
- Sodium chloratePeroxide forming ethers can ignite or explode with strong oxidisers.
- Sodium dichromatePeroxide forming ethers can ignite or explode with strong oxidisers.
- Sulfuric acidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- Thionyl chlorideA leak of corrosive stock can break down flammable containers and feed a fire.
- Zinc chlorideA leak of corrosive stock can break down flammable containers and feed a fire.
Common quantities we collect
Usually held as: neat.
Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.
Where it is commonly held
Hazard statements
- H225 Highly flammable liquid and vapour.
- H315 Causes skin irritation.
- H332 Harmful if inhaled.
- H360FD May damage fertility. May damage the unborn child.
Precautionary statements
- P203 Obtain, read and follow all safety instructions before use.
- P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P233 Keep container tightly closed.
- P240 Ground and bond container and receiving equipment.
- P241 Use explosion-proof electrical, ventilating and lighting equipment.
- P242 Use non-sparking tools.
- P243 Take action to prevent static discharges.
- P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
- P271 Use only outdoors or in a well-ventilated area.
- P280 Wear protective gloves, protective clothing, eye protection and face protection.
- P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P317 Get medical help.
- P318 If exposed or concerned, get medical advice.
- P370+P378 In case of fire: Use suitable extinguishing media to extinguish.
- P403+P235 Store in a well-ventilated place. Keep cool.
- P405 Store locked up.
- P501 Dispose of contents and container in accordance with local, regional, national and international regulations.
- P264 Wash hands and exposed skin thoroughly after handling.
- P302+P352 IF ON SKIN: Wash with plenty of water.
- P321 Specific treatment (see supplemental first aid instruction on this label).
- P332+P317 If skin irritation occurs: Get medical help.
- P362+P364 Take off contaminated clothing. And wash it before reuse.
Substance as classified, dilutions may differ.
Questions
A researcher has left and we found dimethoxyethane on their bench. What now?
Check the dates from the outside, without opening it or moving it to a tidier shelf. If it is old, undated or the cap looks poor, leave it and send an enquiry. Record who used it, if anyone knows, as that history helps the assessment.
Who should be told about dimethoxyethane in our solvent store?
Anyone handling it should know that it may damage fertility and the unborn child, as well as being harmful if inhaled. Your department's safety lead can then make sure it is labelled and that its location is recorded, instead of leaving it in a general cupboard.
Does a septum-capped bottle count as opened once it has been pierced?
Yes, count it as opened from the first piercing, and write that date on the label. Each puncture can let air in, and that is how peroxides start. A bottle pierced many times with no date should stay closed until it has had a specialist assessment.
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