Benzalkonium chloride (CAS 8001-54-5): storage and disposal
Pharmacy compounding rooms, clinic stores, veterinary practices and university labs keep benzalkonium chloride as a solution or a stronger concentrate. It is classified as causing severe skin burns and eye damage, harmful by swallowing, skin contact and inhalation, and very toxic to aquatic life. Weaker preparations may be less hazardous, but the concentrate on the shelf is the stock that decides the arrangements.
- CAS number
- 8001-54-5
- Form
- Solid
- Storage class
- Corrosive
- Signal word
- Danger
- Usual EWC code
- 16 05 06*
Corrosive
Harmful or irritant
Hazardous to the environment
What to do this week
- Check the label is readable and write down the opened date if it is not already there.
- Check it is stored as corrosive stock and apart from the items listed under "Do not store with".
- If you no longer need it, add it to your disposal list so it goes on the next collection.
Safe storage in a school or lab
Keep it low down, on a resistant tray in a ventilated corrosive store. Because it is classed as causing severe burns, a bottle of concentrate stored above head height is the wrong place. Keep the concentrate in compatible, resistant secondary containment, separate from incompatible chemicals, including oxidising chemicals. Storage arrangements should follow the product safety data sheet. A pharmacy that keeps it near alcohol-based antiseptics should move one or the other. Stock arrives as concentrate and as ready-made solution, so label each container with its strength and date, and do not store decanted dilutions in unlabelled bottles beside the concentrate.
How to tell it has deteriorated
Bottles of concentrate in a store show the general corrosive signs: crust at the neck, a cap that has become brittle or stuck, a cracked container, damaged shelving under a leaking bottle and fumes on opening. Do not open a bottle to check for fumes. No characteristic colour change marks its age, so the container is what to check. Look for leaks onto the tray, a faded strength on the label, a bottle with no date, and damaged secondary containment. A bottle that has leaked should be left where it stands and reported, not wiped up and put back.
How it must be disposed of
By specialist collection only. It never goes down the drain or into general waste. It is normally packed in a corrosive other laboratory pack with compatible chemicals.
Begin by recording each container's strength and volume: concentrate and solution are not the same item. The burns classification means the concentrate is handled with care, and nobody should decant or consolidate it on the way out. Because it is very toxic to aquatic life, it never goes to a drain, and a pharmacy or clinic washing remainders away is exactly what to avoid. A veterinary practice uses 18 02 05*, a human healthcare setting 18 01 06*, and a university 16 05 06*. The collection supplier determines compatible packing groups from the products and their classifications, and a registered carrier collects them.
| EWC code, laboratory chemicals | 16 05 06* |
|---|---|
| Discarded organic chemical, not a laboratory pack | 16 05 08* |
| Human healthcare setting | 18 01 06* |
| Veterinary setting | 18 02 05* |
| Hazardous waste | Yes |
The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.
Do not store with
- FlammableA leak of corrosive stock can break down flammable containers and feed a fire.
- OxidiserCorrosive stock can react with oxidisers, releasing heat or fumes.
Named chemicals to keep apart
- AcetoneA leak of corrosive stock can break down flammable containers and feed a fire.
- Calcium hypochloriteCorrosive stock can react with oxidisers, releasing heat or fumes.
- EthanolA leak of corrosive stock can break down flammable containers and feed a fire.
- HexaneA leak of corrosive stock can break down flammable containers and feed a fire.
- Hydrogen peroxideCorrosive stock can react with oxidisers, releasing heat or fumes.
- MethanolA leak of corrosive stock can break down flammable containers and feed a fire.
- Potassium nitrateCorrosive stock can react with oxidisers, releasing heat or fumes.
- Potassium permanganateCorrosive stock can react with oxidisers, releasing heat or fumes.
Show 1 more
- TolueneA leak of corrosive stock can break down flammable containers and feed a fire.
Common quantities we collect
Usually held as: solution, concentrate.
Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.
Where it is commonly held
Hazard statements
- H302 Harmful if swallowed.
- H312 Harmful in contact with skin.
- H314 Causes severe skin burns and eye damage.
- H332 Harmful if inhaled.
- H400 Very toxic to aquatic life.
Precautionary statements
- P260 Do not breathe dust, fume, gas, mist, vapours or spray.
- P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
- P262 Do not get in eyes, on skin, or on clothing.
- P264 Wash hands and exposed skin thoroughly after handling.
- P264+P265 Wash hands and exposed skin thoroughly after handling. Do not touch eyes.
- P270 Do not eat, drink or smoke when using this product.
- P271 Use only outdoors or in a well-ventilated area.
- P273 Avoid release to the environment.
- P280 Wear protective gloves, protective clothing, eye protection and face protection.
- P284 In case of inadequate ventilation wear respiratory protection.
- P301+P316 IF SWALLOWED: Get emergency medical help immediately.
- P301+P317 IF SWALLOWED: Get medical help.
- P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
- P302+P352 IF ON SKIN: Wash with plenty of water.
- P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P316 Get emergency medical help immediately.
- P317 Get medical help.
- P320 Specific treatment is urgent (see supplemental first aid instruction on this label).
- P321 Specific treatment (see supplemental first aid instruction on this label).
- P330 Rinse mouth.
- P361+P364 Take off immediately all contaminated clothing. And wash it before reuse.
- P362+P364 Take off contaminated clothing. And wash it before reuse.
- P363 Wash contaminated clothing before reuse.
- P391 Collect spillage.
- P403+P233 Store in a well-ventilated place. Keep container tightly closed.
- P405 Store locked up.
- P501 Dispose of contents and container in accordance with local, regional, national and international regulations.
Substance as classified, dilutions may differ.
Questions
How should leftover benzalkonium solution be handled after use?
It is classified as very toxic to aquatic life, so leftover solution is collected and never tipped down a sink. Keep it labelled with its strength and list it for specialist collection.
Where in a pharmacy should the concentrate sit?
Low down, on a resistant tray in a ventilated corrosive store, away from flammable stock such as alcohol-based products and from oxidising chemicals. Date it and label the strength clearly.
How do we describe a part-used bottle?
List the strength on the label, the approximate volume left, the condition of the cap and any crust or staining. Do not top up or combine bottles. A leaking container should be left in place and reported.
Is the dilute solution classed the same as the concentrate?
The classification applies to the substance, and a dilute solution may be less hazardous. Do not assume either way. Describe the product by the label and supplier safety data sheet, and let collection staff confirm the entry.
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