Isopropanol: safe storage and disposal
Isopropanol (CAS 67-63-0), widely known as IPA, turns up in almost every kind of lab. Schools hold it for cleaning optics and lab work, pathology departments use it in processing, and clinics buy it in wipes and rubs. Its GHS signal word is Danger. The hazard statements are H225 Highly flammable liquid and vapour, H319 Causes serious eye irritation and H336 May cause drowsiness or dizziness.
- CAS number
- 67-63-0
- Form
- Liquid
- Storage class
- Flammable
- Signal word
- Danger
- Usual EWC code
- 16 05 06*
Flammable
Harmful or irritant
What to do this week
- Leave it where it is. If it looks old, crystalline or damaged, do not open or move it and keep people away from the shelf.
- Write down the label wording, the rough age and where it is stored, from a safe distance.
- Send us those details, and a photo if you can take one without touching it.
Safe storage of isopropanol in a school or lab
Keep bulk isopropanol with flammables, in a fire-resisting cabinet, in its original closed container. Keep what is on the open bench to the amount the job needs, as your DSEAR assessment will expect. Keep it away from ignition sources, and out of domestic fridges.
One detail separates isopropanol from most bench solvents: write the date of opening on the bottle. A twelve-month review interval from opening is used as a prompt to reassess stored isopropanol. That is a prompt for a check drawn from published peroxide former lists. It is not a supplier's expiry date, and it does not mean the bottle has become dangerous on that day.
Squeeze bottles need labels too. A clear liquid in a plastic bottle near a sink is exactly how people end up guessing.
How to tell isopropanol has deteriorated
Most isopropanol in use is turned over quickly and shows no change at all. The cases worth attention are old, opened, part-empty bottles that have spent years in contact with air.
Look for an opened date many years past, crystals or solids around the cap or in the liquid, a thickening or layering of the contents, and a discoloured or swollen container. Any of these means stop. Leave the bottle closed and where it is, keep others away and arrange for a specialist assessment. Do not test it for peroxides or open it to check. A very old undated bottle with no visible change still gets recorded, and it should be discussed before it is moved.
Water uptake and contamination are the more ordinary concerns. A drop in level with no usage suggests a poor seal. Cloudiness suggests the bottle has had something added, so treat it as an uncertain mixture.
This can form peroxides as it ages, especially after opening. Age and the opened date matter more than appearance, so a container with no opened date should be treated as old.
Review after 12 months: Review interval after opening from the cited peroxide former lists, not an expiry date from a manufacturer. Class C and all other chemicals are left null.
How isopropanol must be disposed of
Isopropanol goes by specialist collection. It should not go down a sink or be evaporated as a way of removing it.
| Setting | Usual List of Wastes code | Hazardous |
|---|---|---|
| Laboratory chemical, including school and university | 16 05 06* | Yes |
| Discarded organic chemical, not in a laboratory pack | 16 05 08* | Yes |
| Human healthcare setting | 18 01 06* | Yes |
| Veterinary setting | 18 02 05* | Yes |
The solvents entry 20 01 13* belongs to municipal collections and is not the normal code for a laboratory collection. For transport, isopropanol is UN 1219, packing group II. Products containing it may carry a different UN number, so read the product's data sheet.
A lab that generates regular volumes should think of this as a stream and not as an occasional clear-out. Solvent waste collection covers that type of job, and keeps full containers from sitting in the store.
| EWC code, laboratory chemicals | 16 05 06* |
|---|---|
| Hazardous waste | Yes |
The code depends on where the waste came from and what it is mixed with. Use the waste code finder to see why.
Do not store isopropanol with
- Nitric acid reacts violently with organic solvents and can ignite them, or build pressure in a waste bottle.
- Perchloric acid forms explosive mixtures with organic material.
- Sodium hypochlorite, calcium hypochlorite and other chlorine-releasing disinfectants react with it, releasing heat and chlorinated products. This one catches out clinical areas, where IPA and chlorine disinfectant may sit in the same cleaning cupboard.
- Oxidisers, corrosives and acids as storage classes should be kept separate from flammable stock.
- OxidiserOxidisers can ignite flammable materials or make a fire far more intense.
- AcidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- CorrosiveA leak of corrosive stock can break down flammable containers and feed a fire.
Named chemicals to keep apart
- Acetic acidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- Calcium hypochloriteHypochlorites react with these solvents, releasing heat and chlorinated products.
- Chloramine THypochlorites react with these solvents, releasing heat and chlorinated products.
- Hydrochloric acidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- Hydrogen peroxideOxidisers can ignite flammable materials or make a fire far more intense.
- Nitric acidNitric acid reacts violently with organic solvents and can ignite them or build pressure in waste bottles.
- Perchloric acidPerchloric acid forms explosive mixtures with organic material.
- Potassium nitrateOxidisers can ignite flammable materials or make a fire far more intense.
Show 6 more
- Potassium permanganateOxidisers can ignite flammable materials or make a fire far more intense.
- Sodium dichloroisocyanurateHypochlorites react with these solvents, releasing heat and chlorinated products.
- Sodium hypochloriteHypochlorites react with these solvents, releasing heat and chlorinated products.
- Sulfuric acidOxidising acids can ignite flammable materials, and acid fumes attack containers and seals.
- Thionyl chlorideA leak of corrosive stock can break down flammable containers and feed a fire.
- Zinc chlorideA leak of corrosive stock can break down flammable containers and feed a fire.
Common quantities of isopropanol collected
Expect part-used 500ml and 1 litre bottles, Winchesters in larger labs, and larger containers where a pathology department processes tissue. Clinics may have boxes of wipes or rub past their date, which are a different product and should be listed as such.
Usually held as: neat, 70% wipes and hand rub.
Part-used bottles and full containers are both fine. Tell us the size and how many, and an estimate is enough for a first price.
Isopropanol in different sectors
Schools and colleges. Small stocks, often part-used and undated. Add a date during your next stock check, and write "before" a year if you cannot be precise.
Pathology and histology. Used as a processing alcohol in some labs, alongside ethanol. Keep used solvent apart from clean stock, and list what it may contain. The healthcare classification guidance sets out the chemical codes.
Pharmacy, clinics and dental practices. Expired rubs and wipes appear in stock rotation. They do not belong in the clinical bag merely because they were bought for clinical use.
Veterinary practices. The animal healthcare entry 18 02 05* applies in place of the human healthcare code.
Hazard data from PubChem GHS classification, retrieved 31 October 2026. Guidance only. Check your own risk assessment and your supplier's safety data sheet.
Hazard statements
- H225 Highly flammable liquid and vapour.
- H319 Causes serious eye irritation.
- H336 May cause drowsiness or dizziness.
Precautionary statements
- P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P233 Keep container tightly closed.
- P240 Ground and bond container and receiving equipment.
- P241 Use explosion-proof electrical, ventilating and lighting equipment.
- P242 Use non-sparking tools.
- P243 Take action to prevent static discharges.
- P261 Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264+P265 Wash hands and exposed skin thoroughly after handling. Do not touch eyes.
- P271 Use only outdoors or in a well-ventilated area.
- P280 Wear protective gloves, protective clothing, eye protection and face protection.
- P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P319 Get medical help if you feel unwell.
- P337+P317 If eye irritation persists: Get medical help.
- P370+P378 In case of fire: Use suitable extinguishing media to extinguish.
- P403+P233 Store in a well-ventilated place. Keep container tightly closed.
- P403+P235 Store in a well-ventilated place. Keep cool.
- P405 Store locked up.
- P501 Dispose of contents and container in accordance with local, regional, national and international regulations.
Substance as classified, dilutions may differ.
Questions
Can used isopropanol wipes go in the general bin with other surgery waste?
Not as a default. A lightly used wipe in routine practice may be covered by your clinical waste contract, so check with that contractor, but tubs of unused or part used wipes are chemical stock. They are not for a general bin, and should be listed for specialist collection.
Our isopropanol has no opened date. How do we work out how old it is?
Look for a supplier batch number or a delivery record, and ask who ordered it. If you cannot establish its age, regard it as undated. Do not move or open an undated old bottle, and get a specialist assessment. A recent bottle you can identify can simply be dated and put on the review list.
Does expired hand rub carry the same risk as a bottle of neat solvent?
It is lower risk than bulk solvent but it is still flammable stock, so it should stay in a suitable store and must not be tipped away. A few expired dispensers and a pallet of them also need different handling, so give the quantity when you ask for a collection.
Can we keep the isopropanol waste bottle next to the nitric acid waste?
No. Nitric acid reacts violently with organic solvents and can ignite them or build pressure in a closed waste bottle. Keep the two waste streams well apart, in separate labelled containers and stores. If they may already have been mixed, do not open it, and get specialist advice at once.
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